The concept of presenteeism and its effects in an organization, such as productivity loss, is a subject of intense interest especially in recent years, since organizational scholars are getting more familiar with the concept. The purpose of this thesis was to examine, with the aid of Flight Simulator devices, how this phenomenon affects pilots and flight safety. Data were collected from civil and fighter pilots in Germany, Greece and Italy. Results indicated that pilots performance was affected negatively when they act under presenteeism conditions during critical phases of a flight. Limitations and future research are discussed.