Οστεοπόρωση, κλινική οντότητα, οικονομικές και κοινωνικές επιπτώσεις. Έρευνα κόστους - αποτελεσματικότητας θεραπευτικών παρεμβάσεων
Osteoporosis, clinical entity, economic and social repercussions. Cost - effectiveness survey of therapeutic interventions
Osteoporosis is a metabolic disease that is characterized by low bone mass and micro architectural deterioration of bone tissue with a subsequent increase in bone fragility and susceptibility to fracture. Mainly osteoporotic fractures occur as a consequence of low mechanic energy. The most affected areas are bodies of vertebras, hip, forearm and shoulder. Have been placed quantitative criteria of diagnosis of osteoporosis based on the measurements of bone mass density. Repercussion of osteoporosis, as well as the unfavorable clinical consequences of fractures increases with age, especially in women after the menopause. A variety of agents are available for the treatment of osteoporosis. The evidence for their efficacy and their cost - effectiveness is examined and focused on alendronate, risendronate, raloxifene and teriparatide.