Ανάλυση γονιδιακών εκφράσεων για τη μελέτη του χρόνου επιβίωσης γυναικών με καρκίνου του μαστού
Σπινέλη, Λουκία Δ.
SubjectPolymerase chain reaction -- Methods ; Nucleic acids -- Analysis ; Καρκίνος ; Gene expression -- Statistical methods ; DNA microarrays -- Statistical methods ; Biomedical Research
The purpose of this study is to analyze the data used in biomedical research to study the survival time in women with breast cancer. This is usually done by identifying and analyzing biological tumor markers, based on the gene expressions of patients’ tumor. In this study will be considered real data that exist for a number of genes measured in the tissues of a patient sample, initially appling some methods for clustering genes and then examining the influence of gene expressions in the survival time of patients using the appropriate model from the survival analysis. The methods of gene clustering and the models of survival analysis were studied with the implementation of the programming language R.