Μελέτη κλινικών / διαγνωστικών δεικτών και δημογραφικών χαρακτηριστικών που σχετίζονται με την επιβίωση ασθενών με καρκίνο του μαστού. Μελέτη δεδομένων της βάσης SEER
A study of the clinical / diagnosis markers and demographic characteristics related to survival in patients with breast cancer. SEER based study
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Ουάσινγκτον ; Καρκίνος του μαστού ; Πρόβλεψη χρόνου επιβίωσηςAbstract
Breast cancer is the most common cancer of the female population in the developed countries of the Western world. It begins when the process of cell growth is not carried out normally, resulting in new cells being formed uncontrollably, while cells that have been damaged over time do not fall off. When this happens, the cells can accumulate to form a malignant (cancerous) tumor.
The main objective of this thesis is to study the clinical and diagnostic indicators and the demographic characteristics related to the survival of people suffering from breast cancer. A sample from Washington of 5552 observations drawn from a SEER*Stat software database was used for this study.
The main statistical methods used in the present study are multiple linear regression, logistic regression and the Cox proportional hazard model. Τhe multiple linear regression cannot be applied since the necessary conditions are not met. The use of logistic regression and Cox models reveals that the key clinical and diagnostic indicators as well as the demographic characteristics that play a role in the survival of breast cancer patients, are age, the similarity of cancer cells with the normal cells, the progesterone receptor, the estrogen receptor, the size and location of the tumor, the number of a person's lymph nodes that have cancer, the number of regional tumors examined as well as the number regional tumors that are positive.