Ανάλυση μοριακών δεικτών που σχετίζονται με την ανάπτυξη του καρκίνου της ουροδόχου κύστης

Παπαδημητρίου, Νικόλαος Η.

Master Thesis

Author

Παπαδημητρίου, Νικόλαος Η.

Date

2012-10-03

Abstract

The bladder cancer is a type of cancer that is developed in cells lining the bladder. It is the second most common malignancy of the urinary system, with more than 200.000 new diagnoses and more than 100.000 deaths each year. The ratio of new cases that arise in both sexes, men and women, is 3:1. Usually it affects older people but that does not mean that it does not affect younger people as well. The most common histologic type is transitional cell carcinoma, TCC. The majority of people with the disease are diagnosed at an early stage, where the treatment is effective and we have positive results. However, it is a disease with frequent relapses and so the urologists recommend regular monitoring for several years after the first surgery in order to detect it at an early stage and face it efficiently. The data that we used in our analysis were collected by the Medical School of Athens. We originally used descriptive methods, which allowed us to get a general idea about our data. In the main part of our analysis we went even further by implementing regression analysis and categorical data analysis. Finally, we tried to deal with the missing values in our data and the potential problems they cause to our analysis. Apart from the data analysis, purpose of this paper is also the presentation of scientifically proven results and the comparison with ours as well.