Η σχετιζόμενη με την υγεία ποιότητα ζωής σε ασθενείς με νόσο Crohn και ελκώδη κολίτιδα

Κουλιζάκη, Μαρία

Health-related quality of life in patients with Crohn disease and ulcerative colitis

Master Thesis

Author

Κουλιζάκη, Μαρία

Date

2019

Abstract

This diploma thesis deals with the health-related quality of life in patients who suffer from Crohn's disease and ulcerative colitis. These two diseases belong to Idiopathic Inflammatory Bowel Diseases; they are chronic and recurrent and they affecting the patients both physically and mentally. The aim of this diploma thesis is to evaluate the health-related quality of life of these patients using the EQ5D-3L questionnaire and to identify the factors that affect their quality of life,so that we can understand their needs and design an integrated care system that will cover them. The first part of the diploma thesis, which is the bibliography part, describes the two diseases in detail, as well as the theory of health-related quality of life. The second part of the diploma thesis, which is part of the research, is a statistical analysis of 70 questionnaires answered by patients in the gastrointestinal clinic of Alexandra General Hospital in Attica. The collection of questionnaires lasted from 01/09/2018 to 01/03/2019. The questionnaires, which were given to the patients, were the Greek version of the EQ5D-3L and a questionnaire designed for the purpose of the present diploma thesis containing social, demographic, and diseaserelated characteristics. Results: In the first four dimensions of the EQ5D, patients did not seem to have serious problems, with the exception of the fifth dimension, in which 86% of patients reported to have moderate to excessive anxiety or distress. The Cronbach's Alpha internal consistency coefficient is equal to 0.8276. This means that the reliability of the EQ5D-3L scales is acceptable. The average value of the EQ5D-5L index is 0.746 and the average value of EQVAS is 74.11429. Linear regression analysis showed that active disease was negatively related with HRQL and was statistically significant (p = 0.009) xii and that female gender negatively affected HRQL and this relationship was statistically significant (p = 0.024). Conclusions: The present analysis showed that patients with IIBD reported a lower quality of life than the general population and that active disease and female gender were associated with lower reported HRQL in these patients. In addition, the EQ5D-3L questionnaire is a reliable measurement tool for HRQL in patients with IIBD.

Postgraduate Studies Programme

Οικονομικά και Διοίκηση της Υγείας

Department

Σχολή Οικονομικών, Επιχειρηματικών και Διεθνών Σπουδών. Τμήμα Οικονομικής Επιστήμης

Number of pages

100

Language

Greek

URI

https://dione.lib.unipi.gr/xmlui/handle/unipi/12417

Collections

Τμήμα Οικονομικής Επιστήμης

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