Μελέτη των συμπτωμάτων που βιώνουν οι ασθενείς με καρκίνο πνευμόνων τελικού σταδίου και η επίπτωσή τους στην ποιότητα ζωής τους
Τhis research examines the symptoms experienced by patients with end stage lung cancer and their impact on patients’ quality of life. Specifically, patients with advanced lung cancer completed two quality of life questionnaires (EORTC QLQ-C30, CES-D scale), a symptom assessment questionnaire (ESAS-r) along with demographics. Eighty-nine patients with advanced lung cancer were included in the research, which 13 of them were non valid and excluded from the research. We used parametric and non-parametric tests, Pearson’s Chi-Square test, simple and multiple linear regressions and simple and multiple logistic regressions. We also applied Cronbach’s Alpha Index. The main conclusions are related to the correlation between symptoms experienced by patients and their quality of life. In addition, we studied which of the demographic and clinical factors affect quality of life. High symptomatology increases the overall QLQ-C30 score and decreases the CES-D score. The feeling of pain and tiredness are statistically significant predictors of the overall QLQ-C30 score while the feeling of depression, the type of lung cancer, the type of treatment and the social security status are statistically significant predictors CES-D score. In addition, the symptom of tiredness is a significant predictor of low global health status/quality of life, physical functioning, emotional functioning and cognitive functioning. The symptom of drowsiness is a statistically significant predictor of low role functioning while low social functioning can be predicted by the symptom of tiredness and the treatment type (chemotherapy). The feeling of tiredness and the lack of appetite are valid predictors of patients at risk of depression.