Καρκίνος του τραχήλου της μήτρας και εμβολιασμός. Στάσεις, αντιλήψεις και οικονομική αξιολόγηση
Cervical cancer and vaccination. Attitudes, perceptions and economic evaluation
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Keywords
Καρκίνος του τραχήλου της μήτρας ; HPV ; Προφυλακτικός εμβολιασμός ; Μέθοδοι προσυπτωματικού ελέγχου (screening) ; Οικονομική αξιολόγηση προγραμμάτων υγείας ; Μελέτη κόστους - αποτελέσματοςAbstract
Cervical cancer is one of the most common forms of gynecological cancer in Greece
and worldwide. It’s a difficult equation for the medical community over time but
growing global vaccination coverage seems to be gradually reducing the global
incidence of the disease. The studied oncogenesis in the female reproductive system,
as well as the gradual precancerous lesions in the cervix, are directly related to the
human papillomavirus (Human papillomavirus, HPV), as it has become clear from
years of studies that it is a necessary factor for their appearance. This finding led to
the development of three different vaccines (Gardasil, Cervarix, Gardasil9) given
mainly to young girls, in order to protect them from the high- risk oncogenic types of
the virus that can cause the above adverse conditions.
This work initially seeks a detailed information about cervical cancer, prophylactic
vaccination against it and the cause-and-effect relationship of the disease with the
human papillomavirus. The main purpose, however, evolves in a dual context.
Initially, a questionnaire is attempted to capture the attitudes and perceptions of Greek
women university students about the disease and the vaccine. The second part aims to
present the economic evaluation of vaccination through a review of Greek and
international published research.
The first chapter describes cervical cancer and its causal link to the human
papillomavirus. An attempt is made to analyze in detail the relationship of the virus
with this form of gynecological cancer in order to emphasize the importance of
prevention. The prophylactic vaccination of the virus and consequently of the disease
completes the first chapter as it presents the historical development up to the creation
of the three vaccines, its action, safety, efficacy, acceptance and even the case of male
vaccination against HPV.
The second chapter presents the findings of a questionnaire that was distributed to
213 students of Greek Universities and aimed at capturing the reality of this
population group, for an issue that in Greece is characterized by a lack of data and
information.
The third chapter analyzes the economic evaluation of the prophylactic vaccination
against the disease. The importance of this tool in health economics is initially
emphasized due to its ability to distinguish medical intervention that is cost effective
and at the same time highly effective, using as few financial resources as possible.
Studies are presented that mainly use the cost-effective technique where they compare
the method of vaccination and screening with simple screening. The findings of
international and Greek studies are particularly important and in many cases have
been the basis for the introduction of vaccination into individual health systems in the
effort to treat cervical cancer.